. 2014 Jan 27;9(1):e86332. doi: 10.1371/journal.pone.0086332

Table 3. Effects of SNPs on established cardiovascular risk factors.

				Obesity				Lipid														heart rate		blood pressure					Hypertension			Diabetes
				BMI		W/H		HDL-C mmol/L		LDL-C mmol/L		TC mmol/L		TG mmol/L		apoa1 g/L		apob g/L		apob/apoa1 g/L				SBP mmHg		DBP mmHg
SNP	Chr	Position	Effect allele	β (SE)	P	β (SE)	P	β (SE)	P	β (SE)	P	β (SE)	P	β (SE)	P	β (SE)	P	β (SE)	P	β (SE)	P	β (SE)	P	β (SE)	P		β (SE)	P		OR(95%CI)	P	OR(95%CI)	P
rs10953541	7	107031781	C	−0.14 (0.11)	0.187	0.00 (0.00)	0.706	−0.01 (0.01)	0.546	−0.02 (0.05)	0.638	−0.01 (0.05)	0.750	0.02 (0.04)	0.708	−0.01 (0.01)	0.444	−0.01 (0.01)	0.507	0.00 (0.01)	0.954	−0.23 (0.35)	0.524	0.69 (0.64)	0.280		0.54 (0.36)	0.130		1.09 (0.93–1.30)	0.483	1.19 (0.96–1.47)	0.122
rs1122608	19	11024601	C	0.19 (0.14)	0.177	0.01 (0.00)	0.060	−0.03 (0.02)	0.595	−0.16 (0.06)	0.009	−0.04 (0.06)	0.550	0.13 (0.06)	0.020	−0.03 (0.02)	0.086	−0.00 (0.01)	0.812	0.01 (0.01)	0.499	0.75 (0.44)	0.093	−0.06 (0.81)	0.939		0.52 (0.45)	0.244		0.97 (0.80–1.22)	0.856	0.91 (0.70–1.18)	0.471
rs12190287	6	134256218	G	0.07 (0.09)	0.445	0.00 (0.00)	0.830	0.01 (0.01)	0.545	−0.04 (0.04)	0.236	0.01 (0.04)	0.802	0.02 (0.03)	0.629	0.01 (0.01)	0.532	0.00 (0.01)	0.988	−0.00 (0.01)	0.543	0.48 (0.27)	0.078	−1.18 (0.49)	0.017		−0.14 (0.28)	0.612		0.91 (0.86–1.11)	0.273	1.01 (0.86–1.18)	0.942
rs12413409	10	104709086	G	0.06 (0.09)	0.506	0.01 (0.00)	0.002	0.01 (0.01)	0.423	0.05 (0.04)	0.202	0.01 (0.04)	0.894	−0.06 (0.04)	0.141	0.00 (0.01)	0.766	−0.01 (0.01)	0.520	−0.01 (0.01)	0.227	0.87 (0.30)	0.003	0.21 (0.54)	0.700		0.18 (0.30)	0.554		1.03 (0.88–1.15)	0.755	1.00 (0.85–1.20)	0.989
rs1412444	10	90992907	T	0.08 (0.09)	0.382	0.00 (0.00)	0.634	−0.01 (0.01)	0.439	0.05 (0.04)	0.165	−0.00 (0.04)	0.925	0.01 (0.04)	0.725	−0.01 (0.01)	0.146	−0.00 (0.01)	0.863	0.01 (0.01)	0.378	−0.23 (0.28)	0.419	−0.09 (0.51)	0.858		0.24 (0.29)	0.400		0.95 (0.87–1.12)	0.615	1.03 (0.87–1.21)	0.751
rs1746048	10	44095830	T	0.04 (0.08)	0.649	0.00 (0.00)	0.059	−0.01 (0.01)	0.486	0.04 (0.04)	0.278	0.04 (0.03)	0.273	−0.02 (0.03)	0.581	0.00 (0.01)	0.753	0.01 (0.01)	0.095	0.00 (0.01)	0.904	0.07 (0.26)	0.788	−0.40 (0.48)	0.402		−0.05 (0.27)	0.857		0.91 (0.87–1.12)	0.312	0.93 (0.79–1.09)	0.351
rs3798220	6	160881127	T	0.06 (0.15)	0.682	0.00 (0.00)	0.288	0.02 (0.02)	0.260	−0.12 (0.07)	0.060	−0.02 (0.06)	0.761	0.12 (0.06)	0.040	0.01 (0.02)	0.728	0.01 (0.01)	0.558	0.00 (0.01)	0.681	0.06 (0.47)	0.897	0.86 (0.00)	0.401		0.36 (0.48)	0.452		0.86 (0.77–0.19)	0.312	0.82 (0.66–1.19)	0.451
rs4977574	9	22088574	G	−0.03 (0.09)	0.760	−0.00 (0.00)	0.050	−0.01 (0.01)	0.468	0.03 (0.04)	0.450	0.04 (0.04)	0.270	0.04 (0.03)	0.234	−0.01 (0.01)	0.291	0.01 (0.01)	0.166	0.01 (0.01)	0.108	−0.14 (0.27)	0.592	0.03 (0.49)	0.953		−0.06 (0.28)	0.823		0.90 (0.84–1.08)	0.259	1.01 (0.87–1.18)	0.968
rs579459	9	135143989	C	0.06 (0.10)	0.531	0.00 (0.00)	0.550	−0.01 (0.01)	0.374	0.10 (0.04)	0.020	0.14 (0.04)	0.009	0.02 (0.04)	0.632	0.00 (0.01)	0.700	0.02 (0.01)	0.003	0.02 (0.01)	0.012	−0.54 (0.31)	0.085	−0.54 (0.57)	0.345		−0.28 (0.32)	0.373		1.02 (0.93–1.23)	0.844	1.09 (0.96–1.37)	0.651

Chr, chromosome; β(SE), effect size (standard error); OR(95%CI), odds ratio (95% confidence intervals); BMI, body mass index (kg/m2); cm, centimeters; W/H, waist/hip ratio; HT, hypertension; T2D, type 2 diabetes; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglycerides; TC, total cholesterol; Apo, apolipoprotein.SBP, systolic blood pressure; DBP, diastolic blood pressure.