Table 3.
Radiation-related toxicity stratified by type of radiation administered.
Conformal Radiation | IMRT | IMRT vs. Conformal RT | |||||||
---|---|---|---|---|---|---|---|---|---|
|
|||||||||
N | (%) | 100 Person -Years | Rate | N | (%) | 100 Person -Years | Rate | Rate ratio | |
Late toxicities | |||||||||
Radiation enteritis | 275 | 8.5% | 11.55 | 23.8 | 19 | 5.8% | 0.65 | 29.1 | 1.22 (0.77-1.94) |
Bowel obstruction | 494 | 15.3% | 18.68 | 26.4 | 42 | 12.8% | 1.12 | 37.3 | 1.41 (1.03-1.93)* |
Other gastrointestinal | 176 | 5.5% | 7.18 | 24.5 | 12 | 3.7% | 0.35 | 34.4 | 1,49 (0.78-2.52) |
complications | |||||||||
Genitourinary | 271 | 8.4% | 10.61 | 25.5 | 30 | 9.2% | 0.95 | 31.7 | 1.24 (0.85-1.81) |
complication | |||||||||
Hip fracture | 376 | 11.7% | 16.06 | 23.4 | 32 | 9.8% | 0.99 | 32.4 | 1.38 (0.96-1.99) |
IMRT=intensity-modulated radiation therapy