Table 3. Univariate and multivariate analysis of the categorical and continuous LNR with cause-specific survival (CSS) and overall survival (OS) of SEER laryngeal cancer patients with lymph node metastasis.

LNRclassification	CaseNo.	5-yearCSS(%)	Log-rankχ2 (P )	Multivariate analysis of CSS†			5-yearOS(%)	Log-rankχ2 (P )	Multivariate analysis of OS†
				HR (95% CI)	C-index	AIC			HR (95% CIs)	C-index	AIC
Continuous LNR				2.299(1.905–2.775)	0.658	14037.85			1.810(1.532–2.138)	0.642	18430.78
Cutpoints 0.06/0.23			109.197		0.658	14042.83		87.729		0.642	18432.54
R1: 0–0.06	637	56.3	(<0.001)	Reference			43.9	(<0.001)	Reference
R2: 0.06–0.23	737	42.4		1.270(1.074–1.502)			33.4		1.233(1.070–1.421)
R3: >0.23	589	29.4		1.928(1.635–2.273)			22.2		1.624(1.409–1.871)
Cutpoints 0.09/0.20			125.228		0.661	14027.14		94.673		0.645	18424.27
R1: 0–0.09	860	55.1	(<0.001)	Reference			43.1	(<0.001)	Reference
R2: 0.09–0.20	458	40.2		1.421(1.202–1.680)			31.5		1.308(1.133–1.509)
R3: >0.20	645	28.8		1.962(1.695–2.271)			21.8		1.607(1.416–1.825)

^†The multivariate analysis was adjusted using the same Cox regression model at Table 2.