Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2004 Apr 1;32(6):1973–1981. doi: 10.1093/nar/gkh509

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2004 Oxford University Press

PMC Copyright notice

(a) Cobalamine biosynthetic pathway based on the KEGG database (39). The systematic names of the C.acetobutylicum genes of the cobalamine operon are shown. Conversion of Cob(II)yrinate a,c diamide into Cob(I)yrinate a,c diamide is carried out by CAC0018 (not shown). The gene or genes responsible for the conversion of Cob(I)yrinate a,c diamide into adenosyl cobyrinate a,c diamide are unknown. (b) Genome organization of the B12 TU in C.acetobutylicum. CAC1365, CAC1366, CAC1367 and CAC1368 encode the high-affinity-ATP-dependent cobalt transport system cbiMNQO, CAC1371 encodes an l-threonine kinase needed for the biosynthesis of l-threonine-3P which is a substrate for CobD. The function of CAC1386 is still unknown, but it might encode the conversion of Cob(I)yrinate a,c diamide into adenosyl cobyrinate a,c diamide.

(a) Cobalamine biosynthetic pathway based on the KEGG database (39). The systematic names of the C.acetobutylicum genes of the cobalamine operon are shown. Conversion of Cob(II)yrinate a,c diamide into Cob(I)yrinate a,c diamide is carried out by CAC0018 (not shown). The gene or genes responsible for the conversion of Cob(I)yrinate a,c diamide into adenosyl cobyrinate a,c diamide are unknown. (b) Genome organization of the B12 TU in C.acetobutylicum. CAC1365, CAC1366, CAC1367 and CAC1368 encode the high-affinity-ATP-dependent cobalt transport system cbiMNQO, CAC1371 encodes an l-threonine kinase needed for the biosynthesis of l-threonine-3P which is a substrate for CobD. The function of CAC1386 is still unknown, but it might encode the conversion of Cob(I)yrinate a,c diamide into adenosyl cobyrinate a,c diamide.