Table 2. Comparision of success rate between talc pleurodesis and control therapies at 1 month and longer than 1 month.
Assessing Time | Study/Year | Talc Pleurodesis(n/N) | Control Therapies(n/N) | RR (95% CI) | I2, P (het) | P (Z) |
1 month | ||||||
Lynch/1996 | 8/17 | 18/29 | 0.76 (0.42–1.35) | |||
Diacon/2000 | 13/15 | 10/17 | 1.47 (0.94–2.30) | |||
Ong/2000 | 16/18 | 14/20 | 1.27 (0.91–1.77) | |||
Crnjac/2004 | 27/38 | 40/45 | 0.80 (0.64–1.00) | |||
Haddad/2004 | 33/37 | 30/34 | 1.01 (0.86–1.19) | |||
Paschoalini/2005 | 21/25 | 23/24 | 0.88 (0.72–1.06) | |||
Demmy/2012 | 15/25 | 23/26 | 0.68 (0.48–0.96) | |||
Overall | 133/175 | 158/195 | 0.94 (0.80–1.11) | 58.1%, 0.026 | 0.455 | |
Longer than 1 month | ||||||
Fentiman/1983 | 18/20 | 9/17 | 1.70 (1.06–2.72) | |||
Sorensen/1984 | 9/9 | 7/12 | 1.65 (1.01–2.68) | |||
Fentiman/1986 | 11/12 | 10/21 | 1.92 (1.19–3.11) | |||
Hamed/1989 | 10/10 | 10/15 | 1.45 (1.00–2.12) | |||
Diacon/2000 | 13/15 | 6/17 | 2.46 (1.25–4.82) | |||
Kuzdzal/2003 | 17/18 | 1/13 | 12.28 (1.86–80.98) | |||
Haddad/2004 | 30/37 | 23/34 | 1.20 (0.91–1.59) | |||
Crnjac/2004 | 23/34 | 33/39 | 0.80 (0.61–1.05) | |||
Das/2008 | 19/24 | 24/28 | 0.92 (0.72–1.19) | |||
Mohsen/2011 | 19/22 | 17/20 | 1.02(0.79–1.30) | |||
Davis/2012 | 36/48 | 26/51 | 1.47 (1.07–2.02) | |||
Overall | 205/249 | 166/267 | 1.35 (1.07 − 1.69) | 74.9%, <0.001 | 0.010 |
n = the number of patients with successful pleurodesis; N = the number of evaluable patients for outcome; RR = relative risk;
CI = confidence interval.