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. 2014 Jan 27;9(1):e87060. doi: 10.1371/journal.pone.0087060

Table 2. Comparision of success rate between talc pleurodesis and control therapies at 1 month and longer than 1 month.

Assessing Time Study/Year Talc Pleurodesis(n/N) Control Therapies(n/N) RR (95% CI) I2, P (het) P (Z)
1 month
Lynch/1996 8/17 18/29 0.76 (0.42–1.35)
Diacon/2000 13/15 10/17 1.47 (0.94–2.30)
Ong/2000 16/18 14/20 1.27 (0.91–1.77)
Crnjac/2004 27/38 40/45 0.80 (0.64–1.00)
Haddad/2004 33/37 30/34 1.01 (0.86–1.19)
Paschoalini/2005 21/25 23/24 0.88 (0.72–1.06)
Demmy/2012 15/25 23/26 0.68 (0.48–0.96)
Overall 133/175 158/195 0.94 (0.80–1.11) 58.1%, 0.026 0.455
Longer than 1 month
Fentiman/1983 18/20 9/17 1.70 (1.06–2.72)
Sorensen/1984 9/9 7/12 1.65 (1.01–2.68)
Fentiman/1986 11/12 10/21 1.92 (1.19–3.11)
Hamed/1989 10/10 10/15 1.45 (1.00–2.12)
Diacon/2000 13/15 6/17 2.46 (1.25–4.82)
Kuzdzal/2003 17/18 1/13 12.28 (1.86–80.98)
Haddad/2004 30/37 23/34 1.20 (0.91–1.59)
Crnjac/2004 23/34 33/39 0.80 (0.61–1.05)
Das/2008 19/24 24/28 0.92 (0.72–1.19)
Mohsen/2011 19/22 17/20 1.02(0.79–1.30)
Davis/2012 36/48 26/51 1.47 (1.07–2.02)
Overall 205/249 166/267 1.35 (1.07 − 1.69) 74.9%, <0.001 0.010

n = the number of patients with successful pleurodesis; N = the number of evaluable patients for outcome; RR = relative risk;

CI = confidence interval.