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. 2014 Jan 27;9(1):e87375. doi: 10.1371/journal.pone.0087375

Table 1. Characteristics of Patients with and without Postoperative Cognitive Dysfunction.

POCD n = 8 (29%) No POCD n = 20 p Value
Age (years) 75.9±8.1 71.4±7.2 0.159
≥75 5 (63) 5 (25) 0.136
65≤74 2 (25) 13 (65)
Gender (male/female) 6/2 13/7 1.000
Education (years) 12.6±3.0 10.3±2.2 0.028
Hypertension 5 (63) 15 (75) 0.651
Diabetes mellitus 3 (37) 6 (30) 1.000
Peripheral arterial disease 1 (13) 1 (5) 0.497
History of atrial fibrillation 4 (50) 5 (25) 0.372
Ejection fraction 59.6±12.6 65.8±14.2 0.297
Preoperative medications
Aspirin 5 (63) 13 (65) 1.000
Statins 4 (50) 9 (45) 1.000
β-blockers 4 (50) 6 (30) 0.400
Surgical procedure
CABG 1 (13) 8 (40) 0.061
CABG/Valvular 3 (37) 1 (5)
Valvular 4 (50) 11 (55)
CPB time (min) 202±57 183±74 0.529
Cross-clamp time (min) 116±34 119±41 0.861

Continuous variables are presented as mean ± SD and categorical variables are presented as frequency (percentage). CABG  =  coronary artery grafting; CPB  =  cardiopulmonary bypass.