Figure 2. Area and perimeter values. Line graphs show area (upper panels) and perimeter (lower panels) mean value ± SE at each time point in HCT-8 and HCT-8FUres cells.*P < 0.05, **P < 0.01 ***P < 0.001 vs. 0 h; ^###P < 0.001 vs. 3 h; ^£££P < 0.001 vs. 6 h by ANOVA followed by Bonferroni post-test. Histograms show Area (left panel) and perimeter (right panel) mean value ± S.E., comparing HCT-8 and HCT-8FUres cell lines at each time considered. **P < 0.01; ^#P < 0.0001 by unpaired two-tailed t-test.