Table 1. Hematological analyses of mice immunized with B. subtilis sporesa.
Hematological | BALB/c | C57BL/6 | ||||
parametersb | PBS | Sp | HkSp | PBS | Sp | HkSp |
WBC | 55±31 | 58±13 | 40±12 | 61±11 | 50±17 | 58±11 |
MON | 3.8±3 | 1.3±1.1 | 1.5±1.4 | 1.8±0.9 | 1.6±1.3 | 0.8±0.4 |
LYM | 54±17 | 41±9 | 28±6.3 | 46±9.3 | 35±9.1 | 47±10 |
NEU | 10±2.2 | 15±4.4 | 7.1±1.8 | 7.3±3.1 | 13±8.6 | 9.7±1.1 |
EOS | 0.9±0.6 | 0.6±0.1 | 3.1±3.2 | 4.6±1.7 | 0.2±0.3 | 1.1±0.7 |
Five mice per immunization group were bled 1 day following the final dose.
Blood samples were processed to determine white blood cells (WBC), monocytes (MON), lymphocytes (LYM), neutrophils (NEU) and eosinophils (EOS). All the counts are given in 102 cells/µl.
Data are expressed as the mean ± SD of individual measurements. Differences among groups were not observed after ANOVA and Bonferroni's Multiple Comparison test. The results in this table represent one of two independent experiments.
Sp: B. subtilis WW02 spores; HkSp: Heat-killed B. subtilis WW02 spores.