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. 2014 Jan 27;9(1):e87454. doi: 10.1371/journal.pone.0087454

Table 1. Hematological analyses of mice immunized with B. subtilis sporesa.

Hematological BALB/c C57BL/6
parametersb PBS Sp HkSp PBS Sp HkSp
WBC 55±31 58±13 40±12 61±11 50±17 58±11
MON 3.8±3 1.3±1.1 1.5±1.4 1.8±0.9 1.6±1.3 0.8±0.4
LYM 54±17 41±9 28±6.3 46±9.3 35±9.1 47±10
NEU 10±2.2 15±4.4 7.1±1.8 7.3±3.1 13±8.6 9.7±1.1
EOS 0.9±0.6 0.6±0.1 3.1±3.2 4.6±1.7 0.2±0.3 1.1±0.7
a

Five mice per immunization group were bled 1 day following the final dose.

b

Blood samples were processed to determine white blood cells (WBC), monocytes (MON), lymphocytes (LYM), neutrophils (NEU) and eosinophils (EOS). All the counts are given in 102 cells/µl.

Data are expressed as the mean ± SD of individual measurements. Differences among groups were not observed after ANOVA and Bonferroni's Multiple Comparison test. The results in this table represent one of two independent experiments.

Sp: B. subtilis WW02 spores; HkSp: Heat-killed B. subtilis WW02 spores.