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. 2014 Jan 27;9(1):e87444. doi: 10.1371/journal.pone.0087444

Table 1. IC50 values for cDDP and paclitaxel in NT2-D1 cells pretreated with retinoic acid.

cDDP IC50 µM Fold increase in IC50 induced by pretreatment P Value Paclitaxel IC50 µM Fold increase in IC50 induced by pretreatment P Value
NT2-D1 No pretreatment 0.23±0.01 1 - 0.0018±0.00001 1 -
NT2-D1 pretreated with 0.01 µM RA 0.40±0.04 1.7 <0.01 0.0018±0.00004 1 NS
NT2-D1 pretreated with 0.1 µM RA 3.05±0.61 13.3 <0.01 0.0026±0.00004 1.4 <0.001
NT2-D1 pretreated with 10 µM RA 4.28±0.28 18.6 <0.001 0.11±0.01 61 <0.01