Cumulative incidence function curves for end-stage renal disease (ESRD) in study populations, for all ages and stratified by age at time of diabetes diagnosis. For most First Nations participants, diabetes was diagnosed when they were 60 years of age or younger, when the incidence of ESRD is higher. Conversely, for most non–First Nations participants, diabetes was diagnosed when they were older than 60 years of age, when the incidence of ESRD is lowest. Particularly among First Nations people, men consistently experienced a trend toward higher incidence of end-stage renal disease than women, regardless of age group at time of diagnosis, although the differences for comparisons with small sample sizes were not significant.