Figure 2. Seroprotection and GMT levels after a booster dose of JE-CV. D, day; Y, year; GMT, geometric mean titer; PRNT50, plaque reduction neutralization test; error bars, 95% confidence intervals. One dose of JE-CV was given to eligible children who had previously received a single dose of JE-CV two years earlier. JE neutralizing antibody titers were assessed using a PRNT50. A neutralizing antibody titer of ≥ 10 1/dil is accepted as evidence of protection.11 Results are for the PP (n = 340) for D0, D7, and D28 and for the FAS (n = 339) for Y1.