Figure 1.

Schematic of recurrent oncogenic pathways in Burkitt lymphoma. Shown are pathways that regulate proliferation, growth, and survival of Burkitt lymphomas. Gain-of-function mutations are indicated by + signs and loss-of-function mutations by × signs. (Gray boxes) Potential drugs to block these deregulated pathways. See text for details. (From Schmitz et al. 2012; modified, with permission, from the author.)