Table 2. Association between lipid concentrations and selected single nucleotide polymorphisms.
SNP | Position | Location | Alleles | MAF | HWEa | Total cholesterol Pb |
Triglycerides Pb |
HDL cholesterol Pb |
LDL cholesterol Pb |
rs7923837 | 94471897 | intergene | A/G | 0.198 | 0.991 | 0.137 | 0.019 | 0.715 | 0.449 |
rs2488075 | 94480154 | intergene | T/C | 0.140 | 0.806 | 0.041 | 0.081 | 0.460 | 0.119 |
rs947591 | 94485733 | intergene | C/A | 0.161 | 0.413 | 0.018 | 0.297 | 0.056 | 0.112 |
rs11187146 | 94468335 | intergene | C/G | 0.328 | 0.422 | 0.198 | 0.139 | 0.201 | 0.778 |
rs5015480 | 94455539 | intergene | T/C | 0.162 | 0.950 | 0.991 | 0.216 | 0.753 | 0.367 |
rs4646957 | 94219892 | IDE(intron) | C/T | 0.228 | 0.582 | 0.704 | 0.945 | 0.583 | 0.442 |
rs1111875 | 94452862 | intergene | T/C | 0.258 | 0.623 | 0.339 | 0.579 | 0.501 | 0.144 |
HDL-C: high-density lipoprotein cholesterol; LDL-C: low density lipoprotein cholesterol; MAF: minor allele frequency; SNP: single nucleotide polymorphism. aP value for Hardy-Weinberger equilibrium test. bP value derived from the multiple linear regression with adjustment for sex, age, smoking, drinking and BMI assuming an additive genetic model.