Table 3. Effects of rs7923837, rs2488075 and rs947591 on plasma lipid concentrations.
SNP | C/Ca |
C/Ra |
R/Ra |
Effect (mmol/L) | Pb | |||||
N | Mean level (mmol/L) | N | Mean level (mmol/L) | N | Mean level (mmol/L) | |||||
SNPs associated with TG | ||||||||||
rs7923837 | 2098 | 1.11±0.45 | 1033 | 1.05±0.43 | 127 | 1.08±0.42 | -0.031 (0.013) | 0.019 | ||
SNPs associated with TC | ||||||||||
rs2488075 | 2415 | 4.42±0.80 | 788 | 4.36±0.80 | 62 | 4.28±0.66 | -0.058 (0.028) | 0.041 | ||
rs9475910 | 2292 | 4.41±0.80 | 893 | 4.38±0.82 | 78 | 4.15±0.70 | -0.063 (0.027) | 0.018 |
aC/C, C/R and R/R represent homozygotes for the common allele, and heterozygotes and homozygotes for the rare allele, respectively. bP value for the multiple linear regression with adjustment for sex, age, smoking, drinking and BMI assuming an additive genetic model.