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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Invest Radiol. 2013 Jun;48(6):413–421. doi: 10.1097/RLI.0b013e31827a4a3f

Figure 2.

Figure 2

Longitudinal assessment of N1S1 HSE-luc rat tumor model by 3T FSE T2-weighted MRI and 2D bioluminescence imaging. Axial FSE T2-weighted MR and corresponding 2D BLI image of N1S1 tumor (white arrow) at day 7 (A, D), 14 (B, E) and 21 (C, F) in the same rat. MR images demonstrate a time-dependent increase in tumor size with a corresponding increase in average radiance by 2D BLI. A small focus of luminescent signal was visualized by week 3 (F; white arrow) and determined to be a small intrahepatic metastasis by 3D diffuse luminescence tomography and pathology (Figure S2).