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. Author manuscript; available in PMC: 2014 Jan 28.
Published in final edited form as: Clin Immunol. 2012 Dec 20;146(3):197–206. doi: 10.1016/j.clim.2012.12.002

Figure 1. Common pathways in antiphospholipid syndrome and in atherosclerosis.

Figure 1

APLS and atherosclerosis share several common pathways including production of antibodies to phospholipids, heat shock proteins, and oxidized LDL; endothelial dysfunction; immune cell activation; oxidative stress; platelet activation and thrombus formation.