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. Author manuscript; available in PMC: 2014 Jan 28.
Published in final edited form as: Clin Immunol. 2012 Dec 20;146(3):197–206. doi: 10.1016/j.clim.2012.12.002

Figure 3. Synergistic effects of aPL Abs and TLR7 on pDC maturation.

Figure 3

aPL Abs work synergistically with TLR7 to promote pDC maturation and pro-inflammatory function by activating the NF-κB signaling pathway.