Effect of pretreatment with SB225002 (0.3 mg·kg−1, i.p.), SB366791 (0.3 mg·kg−1, i.p.) or SB225002 co-injected with SB366791 (0.3 mg·kg−1, i.p., each) on bladder wet weight, 24 h (A) or MPO activity, 8 h (B) in cystitis induced by cyclophosphamide (CYP; 200 mg·kg−1, i.p.). Each column represents the mean + SEM of six to eight animals *P < 0.05, significantly different from control (saline) values; #P < 0.05, significantly different from cyclophosphamide values; $P < 0.05, significantly different from SB225002 or SB366791 values (one-way anova followed by Bonferroni's post hoc test).