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. 2013 Dec 23;171(2):498–508. doi: 10.1111/bph.12482

Figure 3.

Figure 3

Reduced hepatic lipid contents and alleviated liver injury in EC-AMPK mice treated with selective COX-2 inhibitors. Wild-type and EC-AMPK mice given a high fat diet were treated with vehicle, celecoxib or nimesulide for a period of 4 weeks. At the end of treatment, parameters including body weight and circulating glucose (A), serum triglyceride and cholesterol levels (B), liver to body weight ratios (LW/BW) and hepatic triglyceride contents (C), as well as serum levels of ALT and AST (D) were measured and presented as percentage comparisons against those from vehicle-treated wild-type mice. *P < 0.05 versus wild-type mice treated with vehicle; #P < 0.05 versus EC-AMPK mice treated with vehicle, n = 3–5.