Table 2.
Relationships between consent preferences and various opinions and beliefs. Odds ratios compare the odds of favoring broad consent, between different belief groups. Categories marked with asterisk are reference categories
| Belief | Opinion about the belief (% who held that opinion) | Favored broad consent (%) | Favored study-by- study consent (%) | Model 2 Odds Ratio (p value) | Model 3 Odds Ratio (p value) |
|---|---|---|---|---|---|
| General Trust in Research | |||||
| “Researchers these days don’t pay enough attention to the moral values of society.” | Disagree (61) | 57 | 43 | 1.07 (.59) | --- |
| * Agree (39) | 47 | 53 | |||
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| “Researchers are dedicated people who work for the good of humanity.” | * Disagree (14) | 42 | 58 | ||
| Agree (86) | 54 | 46 | 1.04 (.81) | --- | |
|
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| “Researchers are biased - they do studies to support what they already believe.” | Disagree (56) | 56 | 44 | 1.13 (.32) | --- |
| * Agree (44) | 49 | 51 | |||
|
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| General Concerns about Privacy | |||||
| “How concerned are you about the privacy of your financial information?” | * Unconcerned (10) | 58 | 42 | ||
| Concerned (90) | 52 | 48 | 0.90 (.63) | --- | |
|
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| “How concerned are you about the privacy of your medical information?” | * Unconcerned (19) | 62 | 38 | ||
| Concerned (81) | 50 | 50 | 0.73 (.89) | --- | |
|
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| “Some [medical] information needs extra privacy protections.” | * Agree (33) | 54 | 46 | ||
| Disagree -all medical information should have the same privacy protections (67) | 52 | 48 | 0.89 (.31) | --- | |
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| Values associated with participating in research generally | |||||
|
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| “Researchers studying genetics will find cures for serious diseases.” | * Disagree (11) | 39 | 61 | ||
| Agree (89) | 54 | 46 | 1.21 (.34) | --- | |
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| Values associated with participating in the proposed research project | |||||
|
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| “The study could lead to improved treatments, cures, and lives saved.” | * Disagree (9) | 30 | 70 | ||
| Agree (91) | 55 | 45 | 2.11 (.002) | 2.20 (.001) | |
|
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| “Participating in the study would make me feel like I was contributing to society.” | * Disagree (17) | 33 | 67 | ||
| Agree (83) | 57 | 43 | 1.79 (.001) | 1.85 (.001) | |
|
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| “Participating in the study would be easy.” | * Disagree (43) | 42 | 58 | ||
| Agree (57) | 60 | 40 | 1.59 (<.001) | 1.59 (<.001) | |
|
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| “If [I] had to give [my] permission for researchers to use [my] samples and information for each research project I would feel bothered.” | * Disagree (77) | 45 | 55 | ||
| Agree (23) | 77 | 23 | 5.18 (<.001) | 5.26 (<.001) | |
|
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| “If [I] had to give [my] permission for researchers to use [my] samples and information for each research project I would feel respected and involved.” | * Disagree (18) | 72 | 28 | ||
| Agree (82) | 48 | 52 | 0.51 (<.001) | 0.54 (<.001) | |
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| Concerns about participation in the proposed research project | |||||
| “How concerned would you be about the following if you were a participant? The government having my samples and information.” | * Unconcerned (24) | 72 | 28 | 1.37 (.04) | 1.28 (.08) |
| Concerned (76) | 46 | 54 | |||
|
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| “How concerned would you be about the following if you were a participant? Researchers having my samples and information.” | * Unconcerned (43) | 68 | 32 | 2.22 (<0.002) | 2.17 (<.001) |
| Concerned (57) | 39 | 61 | |||
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| “How concerned would you be about the following if you were a participant? Protecting my privacy.” | * Unconcerned (8) | 67 | 33 | 1.39 (0.17) | --- |
| Concerned (92) | 51 | 49 | |||
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| “I worry that the study would provide bad news about my health.” | * Disagree (73) | 58 | 42 | 1.41 (.01) | 1.43 (.01) |
| Agree (23) | 40 | 60 | |||
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| “I would be afraid that the information collected by the study could be used against me.” | * Disagree (65) | 62 | 38 | 1.82 (<.001) | 1.79 (<.001) |
| Agree (35) | 35 | 65 | |||
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| “Participating in the study would make me feel like a guinea pig.” | * Disagree (64) | 62 | 38 | 1.47 (.003) | 1.73 (.006) |
| Agree (36) | 37 | 63 | |||
*
Reference group