Table 1.

Characteristics of analysed patients-tissue

Patients	Gender	Age at diagnosis (years)	CRC			MLH1	SPTAN1
			Sporadic MLH1+	Sporadic MLH1-(BRAF V600E)	Lynch syndrome MLH1 mutation
Paraffin embedded tissue
1.	m	63	x	-	-	+++	+++
2.	m	71	x	-	-	+++	+++
3.	m	46	x	-	-	++	++
4.	m	68	-	x	-	-	+
5.	m	50	-	x	-	-	+
6.	f	67	-	x	-	-	+
7.	m	49	-	x	-	-	+
8.	m	49	-	-	c.275_278delCCAG	-	+
					(p.Ala92ValfsX15)
9.	m	57	-	-	c.1731G>A	-	+
					(p.Ser577Ser)
10.	m	49	-	-	c.676C>T	-	+
					(p.Arg226X)
11.	f	44	-	-	c.583A>T	-	+
					(p.Lys195X)
Fresh tissue
12. (N)	m	80	-	-	-	++	+++
12. (T)			-	x	-	-	+

-: deficiency; ++: moderate expression; +++: strong expression; +: weak expression; N: tumour surrounding tissue; T: tumour tissue.