Table 1.

Permissivity of cell lines to RRV infection

Cell line	RPFF	Vero	HEK293	HSG	HSG+NaBut^d	AGS	AGS+NaBut
ORF59 “early gene” expression^a	+^e,^g	+^e,^g	+^g	−^g	+^g	−^g	+^g
Local virus transmission^b	+^e,^g	+^e,^g	+^g	−^g	+^g	−^g	+^g
Production of infectious virions^c	+^e,^f	+^e,^g	+^g	−^g	+^g	nd^h	nd

Positive nuclear immunofluorescence detected with rabbit anti-RV2 ORF59 antiserum

Expanding foci of ORF59-positive cells post infection

Infectious RRV virions in supernatent of post infection, titered on permissive RPFF cells

NaBut= sodium butyrate treated

Bruce et al., (2009)(5)

DesRosiers et al., 1997 (14), Searles et al., 1999 (60), DeWire et al., 2003(15)

This study

nd=not determined.