Table 2.

Summary of cholera vaccines tested using challenge studies

Vaccine Strain	Parent Strain	Protective Efficacy	Reference(s)
Non-Living Oral Vaccines
Whole vibrio	V. cholerae O1 Classical Inaba strain Cairo 48, Classical Ogawa strain Cairo 50, El Tor Inaba strain Phil 6973	56%	Black et al , 198735
Whole vibrio-B subunit	V. cholerae O1 Classical Inaba strain Cairo 48, Classical Ogawa strain Cairo 50, El Tor Inaba strain Phil 6973 + purified cholera toxin B subunit	64%	Black et al, 198735
Live Attenuated Oral Vaccines
Texas Star	V. cholerae O1 El Tor Ogawa	61%	Levine et al , 198439
Peru-15	V. cholerae O1 El Tor Inaba strain isolated in Peru in 1991	93%	Cohen et al, 200240
638	V. cholerae O1 El Tor Ogawa strain C7258	100%	Garcia et al , 200541
JBK70	V. cholerae O1 El Tor Inaba strain N16961	89%	Levine et al , 198842
CVD-111	V. cholerae O1 El Tor Ogawa strain N16117	80.90%	Tacket et al , 199745
CVD-103 HgR	V. cholerae O1 Classical Inaba strain 569B	65–100%	Levine et al , 198843 Losonsky et al , 199351 Tacket et al, 199952 Tacket et al , 199248
Bengal-15	V. cholerae O139 strain MO10	83%	Coster et al , 199556
CVD-112	V. cholerae O139 strain AI1837	84%	Tacket et al , 199546