FIG. 5.

Effects on MSC genomic profiles of treatment with PDGF, TGF-β1, and combination of PDGF and TGF-β1. (A) Heatmap indicates significant changes (false discovery rate P-value≤0.05) in gene expression (black, no change; red, increase; green, decrease) due to serum-free, PDGF, TGF-β1, and combination of PDGF and TGF-β1 (n=3). (B) Venn diagram depicts the number of genes regulated in a soluble factor treatment–specific and –nonspecific manner within each segment (n=3). (C) Regulation of actin-binding proteins (ABPs) in response to soluble factor treatment (n=3). Color images available online at www.liebertpub.com/scd