Figure 3. Crx^Rip/+ retinal photoreceptors lack outer segments and possess very short inner segments.

Transmission EM images in the dorsal-ventral midline plane taken through the central retinas of 1-month-old (A) Crx^+/+ and (B) Crx^Rip/+ mice. mito, mitochondria; nuc, nucleus; olm, outer limiting membrane. Original magnification, ×1,200. Scale bar: 2 μm. (C) Transmission EM images in the dorsal-ventral midline plane taken through the central retinas of 1-month-old Crx^+/+ and Crx^Rip/+ mice, showing the presence of ciliary microtubules in the mutant photoreceptors. CM, ciliary microtubule. Original magnification, ×5,000. Scale bar: 1 μm.