Table 2. Models Obtained from Common Molecular Descriptors Distribution^a.

		confusion matrix
property	intersection point	TP	TN	FP	FN	sensitivity	specificity	MCC	accuracy
H-Acc	2.5b	902	156	385	165	0.85	0.29	0.16	0.66
H-Don	3.5c	1005	108	433	62	0.94	0.20	0.22	0.69
LogP	3	886	334	208	180	0.83	0.62	0.45	0.76
LogS	–4	896	355	186	171	0.84	0.66	0.50	0.78
MR	10	894	373	168	173	0.84	0.69	0.53	0.79
MolWt	300	1013	238	303	54	0.95	0.44	0.48	0.78
N+O	3.5d	883	168	373	184	0.83	0.31	0.16	0.65

^aNote: H-Acc, number of hydrogen bond acceptor; H-Don, number of hydrogen bond donors, LogP, logarithm of partition coefficient (octonal/water); LogS, logarithm of water solubility; MR, molar refractivity, MolWt, molecular weight, N + O, number of nitrogen and oxygen.

^bH-Acc ≤ 2, noninhibitors; H-Acc ≥ 3, inhibitors.

^cH-Don ≤ 3, inhibitors; H-Don ≥ 4, noninhibitors.

^dN+O ≤ 3, noninhibitors; N+O ≥ 4, inhibitors.