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. Author manuscript; available in PMC: 2014 Jan 28.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2011 Jul 1;20(8):1683–1689. doi: 10.1158/1055-9965.EPI-11-0203

Table 5.

Most frequent gene pairs involved in the 110 most significant interactions in common between the U.S. and U.K. study populationsa

Gene 1b Gene 2 Number of

SNPs in Gene 1		 Number of

SNPs in Gene 2		 Frequency of

Interactions
STAT1 STAT4 11 27 40
IL1A IL1B 6 11 29
IFNG IL22 5 12 11
IFNAR1 IFNAR2 11 13 9
IL22RA2 IFNGR1 16 31 5
a

p<10−16; total n=110

b

All significant interactions in common between the U.S. and U.K. study populations are between SNPs in different genes on the same chromosomes.