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. Author manuscript; available in PMC: 2014 Jun 19.
Published in final edited form as: Nature. 2013 Oct 27;504(7480):465–469. doi: 10.1038/nature12719

Figure 2. Co-spreading of Xist RNA and PRC2.

Figure 2

a, Normalized read densities of Xist, EZH2, and H3K27me3 on chrX in d7 cells. b, Xist densities (200 kb bins) correlated with EZH2, H3K27me3 and H3K4me3 signals at different stages of XCI. Pearson's r displayed. EZH2/H3K27me3 R2 values: 0.3/0.37 for d0, 0.77/0.88 for d7, and 0.23/0.66 for MEFs, respectively. H3K4me3 R2 values: < 0.15 across all samples.