Table I. Baseline Characteristics.
| Subject ID | Age (Years) | Baseline HbF % | Thalassaemia Mutations | HMIP* Rs9399137 | BCL11A Rs766432 | HBG2Xmn-1 Rs7482144 |
|---|---|---|---|---|---|---|
| 001 | 23 | 20 | IVS I-6/IVS I-6 (T>C) | (N/N) | (N/+) | (N/N) |
| 002 | 39 | 7.9 | IVS I-6/IVS I-6 (T>-C) | (N/N) | (N/N) | (N/N) |
| 003 | 32 | 20 | IVS I-110 G>A, IVS II-1G>A | (N/N) | (+/+) | (N/+) |
| 004 | 21 | 58 | IVS I-6/IVS I-110 | (N/N) | (N/+) | (N/N) |
| 005 | 36 | 25 | IVS I-6/IVS I-6 (T>C) | (N/+) | (N/N) | (N/N) |
| 008 | 25 | 20 | IVS I-6/IVS I-6 | (N/N) | (N/N) | (N/N) |
| 009 | 52 | 17 | (T>C)CD29/CD29 | (N/+) | (N/N) | (N/N) |
| 011 | 27 | 9.8 | IVS I-6/IVS I-6 (T>C) | (N/N) | (N/N) | (N/N) |
| 012 | 25 | 15 | IVS I-6/IVS I-6 (T>-C) | (N/+) | (N/N) | (N/N) |
| 013 | 18 | 54 | IVS I-6/IVS I-6 (T>-C) | (N/+) | (N/N) | (N/N) |
For rs9399137, N designates the major allele, T; + designates the minor allele, C.
For rs 766432, N designates the major allele, A; + designates the minor allele, C.
*
HMIP = HBS1L–MYB intergenic polymorphism.