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Changes from baseline in % HbF (top panel) and total Hgb (bottom panel) in the 3 dose cohorts.
A. Changes in % HbF are shown in individual subjects in each of the 4 treatment groups. Open symbols represent values in subjects on concomitant hydroxyurea treatment.
B. Changes from baseline in total Hgb are shown in individual subjects in each of the 4 treatment groups. Open symbols represent values in subjects on concomitant hydroxyurea treatment.
