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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Mol Cell Neurosci. 2013 Nov;57:73–82.

Figure 1. pGSN protection of gp120-induced neuronal damage.

Figure 1

(A) Dose-dependent toxicity of gp120 on cortical neurons. Exposure of neuronal cells to gp120 at and greater than 500pM resulted in maximal reduction in cell viability. (B) Neurons were treated with 500 pM gp120 and different concentrations of GSN for 24 h. pGSN significantly protected neurons from gp120-mediated damage at a concentration of 2.5 µg/ml. Heat (boiled) inactivated pGSN (indicated by a symbol §, the same as in other figures) failed to produce protective effect. Data represent mean ± SEM from at least 5 independent experiments and expressed as % of control. ** p <0.01 vs. control; # p<0.05 vs. gp120 (0 GSN).