Cultures were treated without or with 50pM, 100pM gp120 respectively 24h. (A) Representative current traces evoked by voltage protocol (upper left, not proportional to the current traces in duration) from three different neurons treated without (Ctrl) or with 50pM, 100pM gp120 respectively for 24h. Note gp120 at 100pM increased outward K+ currents. (B) Instantaneous and steady-state current densities measured at +80mV from groups of neurons treated without (Ctrl, n=15) or with 50pM gp120 (n=13), 100pM gp120 (n=18). Note that gp120 increased both instantaneous and steady-state outward K+ currents at 100 pM. ** p<0.01 vs. control.