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. 2014 Jan 23;9:653–668. doi: 10.2147/IJN.S54911

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© 2014 Legut et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Mitoxantrone (MIT) cytotoxicity for the normal human dermal fibroblast cell line 48 hours (A) and 72 hours (B) after the addition of the free drug or liposomes. Differences between vitamin C anacardic acid liposome (vit C AA lip) and ammonium sulfate (AS) AA lip MIT and between vit C cholesterol (CHOL) lip MIT and AS CHOL lip MIT are significant for the entire range of MIT concentrations, unless indicated otherwise (P<0.05).

Notes: *Other significant differences (P<0.05). Detailed explanation in the text. n=6.

Abbreviation: ns, not significant.