Table 3. Frequency of FoxO1 and FoxO3 polymorphism in CHD from two different populations.

		Subjects from Population 1			Subjects from Population 2			Combined subjects
SNP	genotype	CHD	Non-CHD	P	CHD	Non-CHD	P	CHD	Non-CHD	P
rs2755209	CC	403	423	0.269	221	223	0.836	624	646	0.234
	CA	319	301		209	199		528	500
	AA	86	105		33	36		119	141
Allelic A frequency		0.304	0.308		0.297	0.296		0.301	0.303
rs2721072	AA	360	399	0.285	219	207	0.245	579	606	0.263
	AG	342	336		179	199		521	535
	GG	106	94		65	52		171	146
Allelic G frequency		0.343	0.316		0.334	0.331		0.339	0.321
rs4325427	TT	378	392	0.393	226	220	0.759	604	612	0.322
	TC	326	348		185	192		511	540
	CC	104	89		52	46		156	135
Allelic C frequency		0.330	0.317		0.312	0.310		0.324	0.325
rs17592371	CC	380	387	0.986	218	202	0.651	598	589	0.794
	CT	297	308		181	191		478	499
	TT	131	134		64	65		195	199
Allelic T frequency		0.346	0.347		0.334	0.350		0.341	0.348
rs768023	AA	579	565	0.087	307	301	0.937	886	866	0.243
	AG	176	218		136	135		312	353
	GG	53	46		20	22		73	68
Allelic G frequency		0.175	0.187		0.190	0.195		0.180	0.189
rs1268165	TT	484	515	0.424	301	302	0.526	785	817	0.247
	TC	296	280		142	130		438	410
	CC	28	34		20	26		48	60
Allelic C frequency		0.218	0.210		0.197	0.199		0.210	0.206

Calculations are performed with comparison of three different genotypes. Values are the number of subjects. No significant difference (chi-square test) was found in the frequency of either polymorphism between CHD cases and non-CHD controls.