Table 2.
Clinical and biochemical characteristics of patients with FCHL according to vitamin D status
| Deficient (n = 46) | Sufficient (n = 13) | P | |
|---|---|---|---|
| Age (years) |
51.7 ± 10.3 |
44.9 ± 14.5 |
0.061 |
| BMI (Kg/m2) |
28.2 ± 4.0 |
26.8 ± 4.0 |
0.289 |
| Waist (cm) |
96.2 ± 10.1 |
93.3 ± 12.8 |
0.412 |
| HbA1c (%) |
5.6 ± 0.5 |
5.6 ± 0.4 |
0.838 |
| HOMA |
2.7 ± 2.4 |
1.8 ± 0.9 |
0.838 |
| Total cholesterol (mmol/L) |
6.6 ± 1.6 |
7.1 ± 1.3 |
0.335 |
| Triglycerides (mmol/L) |
2.5 (1.1-15.8) |
2.0 (1.2-3.1) |
0.041 |
| LDL-c (mmol/L) |
3.9 ± 1.2 |
4.8 ± 1.3 |
0.025 |
| HDL-c (mmol/L) |
1.1 ± 0.4 |
1.3 ± 0.3 |
0.051 |
| VLDL-c (mmol/L) |
1.1 (0.5-7.6) |
0.9 (0.6-1.3) |
0.079 |
| NEFA (mmol/L) |
0.7 (0.3-4.3) |
0.5 (0.2-1.1) |
0.015 |
| ApoB (g/L) |
1.3 ± 0.3 |
1.4 ± 0.3 |
0.116 |
| LDL size (nm) |
25.4 ± 0.7 |
25.7 ± 0.4 |
0.184 |
| CRP (mg/L) |
1.6 (0.3-21.1) |
1.5 (0.2-21.5) |
0.901 |
| 25(OH)D (nmol/L) | 48.2 ± 14.3 | 96.9 ± 11.7 | 0.000 |
P values according to T-test and Mann–Whitney test.
FCHL: Familial combined hyperlipidemia, BMI: body mass index, HbA1c: glicated haemoglobin, HOMA: homeostasis model assessment, LDL-c: low-density lipoprotein cholesterol, HDL-c: high-density lipoprotein cholesterol, VLDL-c: very low-density lipoprotein cholesterol, NEFA: non-esterified fatty acids, ApoB: apolipoprotein B, CRP: C-reactive protein, 25(OH)D: 25-hydroxyvitamin D.
Vitamin D deficiency = 25(OH)D ≤ 80 nmol/L.