Table 4. The association of SNPs with CAD risk in additive inheritance mode.
| SNPs | CAD-positive (n = 425) | CAD-negative (n = 258) | P | OR | 95%CI | Pa | ORa | 95%CIa | |
| rs6230 | |||||||||
| CC | 36(8.5) | 13(5.0) | CC: CT | 0.10 | 1.75 | 0.89–3.44 | 0.30 | 1.54 | 0.68–3.48 |
| CT | 179(42.1) | 113(43.8) | CC: TT | 0.10 | 1.74 | 0.89–3.40 | 0.39 | 1.19 | 0.80–1.77 |
| TT | 210(49.4) | 132(51.2) | CT: TT | 0.98 | 1.00 | 0.73–1.38 | 0.69 | 1.09 | 0.72–1.63 |
| rs6233 | |||||||||
| CC | 28(6.6) | 15(5.8) | CC: CT | 0.85 | 1.07 | 0.54–2.10 | 0.52 | 1.37 | 0.52–3.59 |
| CT | 166(39.0) | 95(36.8) | CC: TT | 0.60 | 1.20 | 0.62–2.31 | 0.60 | 1.14 | 0.71–1.82 |
| TT | 231(56.4) | 148(57.4) | CT: TT | 0.50 | 1.12 | 0.81–1.55 | 0.99 | 1.00 | 0.67–1.49 |
| rs6234 | |||||||||
| GG | 40(9.4) | 35(13.6) | GG: GC | 0.134 | 0.68 | 0.41–1.13 | 0.09 | 0.59 | 0.32–1.08 |
| GC | 197(46.4) | 117(45.3) | GG: CC | 0.09 | 0.64 | 0.39–1.08 | 0.06 | 0.74 | 0.54–1.01 |
| CC | 188(44.2) | 106(41.1) | GC: CC | 0.76 | 0.95 | 0.68–1.32 | 0.63 | 0.90 | 0.59–1.37 |
| rs156019 | |||||||||
| AA | 82(19.3) | 51(19.8) | AA: AT | 0.25 | 1.28 | 0.84–1.94 | 0.11 | 1.54 | 0.91–2.58 |
| AT | 224(52.7) | 109(42.2) | AA: TT | 0.21 | 1.32 | 0.85–2.06 | 0.553 | 1.18 | 0.68–2.04 |
| TT | 119(28.0) | 98(38.0) | AT: TT | 0.003 | 1.69 | 1.19–2.40 | 0.04 | 1.92 | 1.23–3.00 |
| rs3811951 | |||||||||
| GG | 35(8.2) | 39(15.1) | GG: AG | 0.02 | 0.54 | 0.32–0.89 | 0.02 | 0.47 | 0.24–0.90 |
| GA | 191(45.0) | 114(44.2) | GG: AA | 0.004 | 0.47 | 0.28–0.79 | 0.008 | 0.64 | 0.46–0.89 |
| AA | 199(46.8) | 105(40.7) | AG: AA | 0.47 | 0.88 | 0.64–1.23 | 0.65 | 0.90 | 0.57–1.41 |
CAD: coronary artery disease; OR: odds ratio; CI: confidence interval. ORa, CIa and P a reperesent OR, CI, p after adjustment for gender, age, BMI and smoking history. Chi square test was used to evaluate OR, 95%CI and P value. multiple logistic regression analysis was used to analyze ORa, 95%CIa and P a.