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. 2014 Jan 28;9(1):e87280. doi: 10.1371/journal.pone.0087280

Table 4. Reference values for pulse oximetry recordings in healthy term neonates during their first 5 days of life for 7 different averaging times and three SpO2 thresholds.

SpO2 Based on ‘SIQ’ definition Based on ‘SIQ & PW’ definition
Threshold (%) T (sec) Median 75th Centile 95th Centile Maximum Median 75th Centile 95th Centile Maximum
90 3 1.78 4.61 15.52 47.14 0.78 2.50 8.38 36.43
5 1.14 2.95 9.92 30.14 0.50 1.60 5.36 23.29
8 0.75 1.95 6.57 19.97 0.33 1.06 3.55 15.43
10 0.62 1.61 5.41 16.42 0.27 0.87 2.92 12.69
12 0.53 1.37 4.61 14.00 0.23 0.74 2.49 10.82
14 0.46 1.20 4.03 12.23 0.20 0.65 2.17 9.45
16 0.41 1.06 3.58 10.88 0.18 0.58 1.93 8.41
85 3 0.00 0.42 1.74 15.00 0.00 0.21 1.07 11.19
5 0.00 0.25 1.07 9.22 0.00 0.13 0.66 6.88
8 0.00 0.16 0.68 5.89 0.00 0.08 0.42 4.39
10 0.00 0.13 0.55 4.76 0.00 0.07 0.34 3.55
12 0.00 0.11 0.46 4.00 0.00 0.06 0.29 2.98
14 0.00 0.10 0.40 3.45 0.00 0.05 0.25 2.58
16 0.00 0.08 0.35 3.04 0.00 0.04 0.22 2.27
80 3 0.00 0.00 0.54 2.32 0.00 0.00 0.39 1.74
5 0.00 0.00 0.31 1.34 0.00 0.00 0.22 1.00
8 0.00 0.00 0.19 0.80 0.00 0.00 0.14 0.60
10 0.00 0.00 0.15 0.63 0.00 0.00 0.11 0.47
12 0.00 0.00 0.12 0.52 0.00 0.00 0.09 0.39
14 0.00 0.00 0.10 0.44 0.00 0.00 0.07 0.33
16 0.00 0.00 0.09 0.38 0.00 0.00 0.06 0.28

The basic values are based on a clinical study where an averaging time of 2–4 s has been used for desaturations with an arbitrary minimal duration. When applying our formula the reference values for 6 other averaging times could be calculated (SIQ: signal quality indicator; PW: pulse waveform; SpO2: pulse oximeter saturation; T (sec): Averaging time in seconds.