Figure 2).

Treatment algorithms for coinfected patients. ^*Standard stopping rules apply (telaprevir [T]: HCV RNA >100 IU/mL at week 4 and 12, detectable at week 24; boceprevir [BOC]: HCV RNA >1000 IU/mL at week 12, detectable at week 24); ^†Standard stopping rules apply: lack of early virological response at week 12, detectable hepatitis C virus (HCV) RNA at week 24. 4, 12, 24, 48 refer to weeks of therapy; PI Protease inhibitor; PR Pegylated inter-feron/ribavirin; RVR Rapid virological response (undetectable HCV RNA)