TABLE 3.

Current recommendations in international guidelines for HIV treatment initiation in hepatitis C virus (HCV) coinfected individuals

Guidelines, year (reference)	HCV coinfection	Class/Grade of evidence
IAS-USA Guidelines, 2012 (66)	ART regardless of CD4 cell count	BIIa
US DHHS Guidelines, 2012 (67)	ART regardless of CD4 cell count	BII
British HIV Association Guidelines, 2012 (68)	ART if CD4 count <500 cells/μL	IC
European AIDS Clinical Society Guidelines, 2012 (69)	ART if CD4 count <500 cells/μL; ≥500 cells/μL: consider ART if HCV therapy not feasible

ART Antiretroviral therapy; IAS-USA International Antiviral Society – United States; US DHHA United States Department of Health and Human Services