TABLE 4.

Baseline assessment of coinfected patients

	Test	Comment
Viral hepatitis screens	HCV antibody
	Quantitative HCV RNA
	HCV genotype
	Hepatitis B surface antigen	Chronic HBV infection
	Hepatitis B surface antibody	Immunity to HBV
	Hepatitis B core antibody
	Hepatitis A immunoglobulin G	Indicates need for HAV vaccine
Liver-related	Complete blood count	Thrombocytopenia may indicate advanced liver disease
	Alanine aminotransferase; aspartate aminotransferase; alkaline phosphatase; gamma-glutamyltransferase
	Albumin, international normalized ratio, total bilirubin	Abnormalities suggest advanced liver disease
	Ultrasound
Screens for other chronic conditions of liver disease	Alpha-1-antitrypsin	Alpha-1-antitrypsin deficiency
	Antinuclear antibody, anti-smooth muscle antibody	Autoimmune hepatitis
	Antimitochondrial antibody	Primary biliary cirrhosis
	Ceruloplasmin	Wilson disease
	Ferritin, iron studies	Hemochromatosis
	Immunoglobulins A, G and M	Autoimmune hepatitis, primary biliary cirrhosis, alcoholic liver disease

HAV Hepatitis A virus; HBV Hepatitis B virus; HCV Hepatitis C virus