Table 3. Formulations studied and their total carrier surface coverage (CC) by fine components.

Formulation	CC (%)*
0.4% Bud	28
4% Bud	283
0.4% Bud +4% FLF	217
0.4% Bud +4% CLF	124
4% Bud +4% FLF	471
4% Bud +4% CLF	378

^*The carrier surface coverage is calculated as explained previously [21]. For these calculations, the X₅₀-values of the fine components from Table 2 were used and densities of budesonide and alpha-lactose monohydrate were considered to be 1.25 [6] and 1.53 g/cm³, respectively. The calculated values are based only on added fine components (drug and lactose fines) and do not take into account the presence of lactose fines intrinsic to the carrier material after the sieving procedure.