Table 2.

Logistic regression models of complete response and complete or any response (complete or partial response) after neoadjuvant chemotherapy and radical cystectomy adjusted for age, gender, clinical stage (T3/4 vs. T2), age-adjusted Charlson score (0–2, 3–4, 5+), and smoking characteristics included individually

	Complete responsea		Complete or partial responseb
	OR (95 %CI)	p value	OR (95 % CI)	p value
Smoking status
Age (per 10 years)	1.14 (0.58, 2.27)	0.7	1.07 (0.64, 1.79)	0.8
Male	0.75 (0.23, 2.47)	0.6	1.20 (0.48, 3.01)	0.7
Clinical stage (T3/4 vs. T2)	0.17 (0.04, 0.66)	0.011	0.27 (0.12, 0.63)	0.003
Charlson score		0.8		0.9
0–2	Ref.	-	Ref.	-
3–5	0.95 (0.25, 3.60)	-	1.04 (0.37, 2.88)	-
5+	2.31 (0.19, 28.62)	-	0.53 (0.05, 5.74)	-
Smoking status		0.5		0.2
Never	Ref.	-	Ref.	-
Former	0.50 (0.15, 1.73)	-	0.88 (0.34, 2.27)	-
Active	0.95 (0.29, 3.16)	-	]2.04 (0.76, 5.51)	-
Packs per day
Age (per 10 years)	1.07 (0.55, 2.07)	0.8	0.99 (0.60, 1.63)	0.9
Male	0.70 (0.22, 2.22)	0.5	1.11 (0.46, 2.68)	0.8
Clinical stage (T3/4 vs. T2)	0.16 (0.04, 0.64)	0.009	0.27 (0.12, 0.62)	0.002
Charlson score		0.8		0.8
0–2	Ref.	-	Ref.	-
3–5	1.02 (0.27, 3.85)	-	0.99 (0.37, 2.70)	-
5+	2.38 (0.19, 29.93)	-	0.50 (0.05, 5.44)	-
Packs per day	0.65 (0.35, 1.20)	0.2	0.88 (0.58, 1.31)	0.5
Pack-years
Age (per 10 years)	1.07 (0.55, 2.07)	0.8	0.99 (0.60, 1.63)	0.9
Male	0.64 (0.20, 2.01)	0.4	1.08 (0.45, 2.60)	0.9
Clinical stage (T3/4 vs. T2)	0.16 (0.04, 0.64)	0.009	0.27 (0.12, 0.62)	0.002
Charlson score		0.8		0.8
0–2	Ref.	-	Ref.	-
3–5	0.99 (0.26, 3.70)	-	0.97 (0.36, 2.62)	-
5+	2.35 (0.18, 30.07)	-	0.47 (0.04, 5.23)	-
Pack-years (per 10 years)	0.92 (0.77, 1.09)	0.3	1.00 (0.89, 1.13)	0.9

^aComplete response (pT0)

^bPartial response (pTis or pT1)

OR odds ratio, CI confidence interval