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Figure 5. ObR+ cells maintains self-renewal dependent on STAT3 signaling pathway. (A) Western blot analysis of p-STAT3, SOX2, and OCT4 in ObR+ cells and U87R cells treated with NSC74859-STAT3 inhibitor. Does of STAT3 inhibitor was indicated on the top. (B) Western blot analysis of SOX2, OCT4, and ObR in ObR+ cells expressing SOX2 or OCT4 siRNA.
