Figure 6. STAT3 inhibitor potentiated TMZ efficacy in glioma cells with high expression of ObR. (A) MTT assay of ObR+ cells treated by STAT3 inhibitor and TMZ. Error bars represent SD of 3 independent experiments.*P < 0.05 vs. TMZ (0). (B) MTT assay of U87R cells treated by STAT3 inhibitor and TMZ. Error bars represent SD of 3 independent experiments.*P < 0.05 vs. TMZ (0). (C) FACS was used to analyze the apoptosis of ObR+ cells treated by STAT3 inhibitor (200 μM) and TMZ (100 μM). *P < 0.05 iii vs. i, # P < 0.05 iv vs. iii.