Table 2.
Concentrations of plasma and erythrocyte lipids and plasma apolipoproteins
| Variable | Normolipidemic group (n = 64) | Hypercholesterolemic group (n = 42) | Mixed-type dyslipidemic group (n = 42) |
|---|---|---|---|
| TC (mg/dL) | 164 ± 24 | 249 ± 25a*** | 242 ± 28b*** |
| TG (mg/dL) | 94 (84–99) | 108 (99–120) | 239 (228–272)b***,c*** |
| LDL-C (mg/dL) | 104 ± 24 | 158 ± 27a*** | 157 ± 30b*** |
| HDL-C (mg/dL) | 44 (40–48) | 50 (47–60)a** | 37 (35–41)b**,c*** |
| VLDL-C (mg/dL) | 41(35–42) | 52 (49–61)a*** | 59 (52–65)b*** |
| Apo B (mg/dL) | 91 ± 20 | 121 ± 26a*** | 130 ± 29b*** |
| Apo AI (mg/dL) | 148 ± 27 | 157 ± 28a*** | 135 ± 2c*** |
| Lp (a) (g/L) | 16 (15–35) | 25 (24–62) | 20 (8–42) |
| Apo E (mg/dL) | 4.1 (3.8–4.6) | 4.0 (3.7–4.6) | 5.8 (5.1–6.0)b***,c*** |
| Buoyant LDL-C (mg/dL) | 50 (36–49) | 39 (37–55) | 37 (34–43) |
| sdLDL-C (mg/dL) | 4 (5–10) | 7 (10–26) | 42 (37–56)b***,c** |
| Mean LDL size (Å) | 268 (267–269) | 268 (264–268) | 263 (260–272)b***,c* |
| LHDL-C (mg/dL) | 13 (15–18) | 17 (16–22) | 10 (9–13)b***,c*** |
| SHDL-C (mg/dL) | 5 (5–7) | 8 (6–9)a** | 6 (4–7)c* |
| Erythrocyte cholesterol (μg/mg prt.) | 436 ± 135 | 461 ± 205 | 490 ± 221 |
| Inorganic phosphate (μg/mg prt.) | 703 ± 32 | 716 ± 34 | 712 ± 31 |
Data are presented as mean ± SD for normally distributed and as median (IQR) for nonnormally distributed continuous variables
Comparison of normolipidemics with hypercholesterolemics (a), mixed-type dyslipidemics (b), and hypercholesterolemics with mixed-type dyslipidemics (c)
*p < 0.0 5, **p < 0.01, ***p < 0.005