Table 4.
Adverse event | Grade: no. of patients | ||||
---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | |
Nonhematologic toxicity | |||||
Hypertension | 2 | 6 | 1 | 1 | – |
Infection | – | – | – | – | – |
Wound dehiscence | – | – | 3 | – | – |
Fatigue | 18 | 5 | 2 | – | – |
Proteinuria | 7 | 10 | – | – | – |
Rash | – | – | – | – | – |
Hyperpigmentation | 2 | – | – | – | – |
Nausea/vomiting | – | – | – | – | – |
Hypophonia | 5 | – | – | – | – |
GI perforation/fistula | – | – | – | – | – |
Hemorrhage, CNS | 2 | – | – | – | 1 |
Hemorrhage, GI | – | 1 | 1 | – | – |
Epistaxis | 2 | – | – | – | – |
Stroke | – | – | – | 1 | – |
DVT | – | – | 2 | – | – |
PE | – | – | – | 2 | – |
Transaminase elevation | – | – | – | – | – |
Hematologic toxicity | |||||
Anemia | 2 | – | – | – | – |
Neutropenia | 1 | 4 | 7 | 1 | – |
Thrombocitopenia | 3 | 8 | 5 | 1 | – |