Table 1. Sociodemographic and clinical information.
| Controls (N=75) | Cases (N=68) | P-value |
rs1344706 |
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|---|---|---|---|---|---|---|---|
| AA (N=66) | AC (N=54) | CC (N=23) | P-value | ||||
| Age | 26.1 (10.5) | 26.4 (12.0) | NS | 27.0 (11.8) | 25.3 (10.6) | 26.2 (11.4) | NS |
| Male/Female | 46/29 | 49/19 | NS | 40/26 | 39/15 | 16/7 | NS |
| Premorbid IQ | 114.6 (15.4) | 110.9 (16.3) | NS | 111.0 (15.1) | 115.6 (15.4) | 111.8 (18.7) | NS |
| Current IQ | 117.8 (14.0) | 110.3 (15.0) | <0.01 | 110.8 (15.5) | 118.4 (12.4) | 114.4 (16.9) | <0.05 |
| Education | 13.9 (2.7) | 12.9 (2.7) | <0.05 | 13.5 (2.7) | 13.4 (2.8) | 13.4 (2.7) | NS |
| pSES | 1.8 (0.9) | 2.1 (1.0) | <0.05 | 2.2 (1.1) | 1.7 (0.77) | 1.91 (0.9) | <0.05 |
| GAF | 84.5 (7.7) | 49.2 (11.0) | <0.01 | 66.0 (20.5) | 70.9 (19) | 62.7 (20.9) | NS |
| CPZ equivalents | NA | 248.8 (214.7) | NA | 343.1 (269.6) | 160.2 (118.8) | 189.3 (123.6) | NS |
Abbreviations: CPZ, chlorpromazine; GAF, global assessment of functioning; NA, not applicable; NS, not significant; pSES, parental socioeconomic status. CPZ equivalents were calculated for subjects on antipsychotic medication (N=36, including 9 CHR, 14 FESZ and 13 CSZ subjects). Values are mean (s.d.). Fisher's Exact Test was used for categorical variables and ANOVA for continuous variables (P>0.05).