Table 2.

Diarrhea in infant rabbits inoculated with C227 or isogenic sigA point mutants

Straina	C227	sigAwt	sigAsp	sigAcl
Diarrhea (%)b	73	67	71	17
Disease category (#)c
Diarrhea	30	4	5	3
Intestinal fluid	9	2	1	8
No gross disease	2	0	1	7
Total no. animals	41	6	7	18
P-value vs C227d	-	1	1	1.18E-4

^aAll strains, except C227, are derivatives of C227⊗sigA, where the sigA deletion was replaced with sigA^wt, sigA^sp or sigA^cl. The C227 data is from Table 1.

^bPercentage of rabbits that exhibited diarrhea by day 3 PI.

^cNumber of rabbits within each category as described in the methods.

^dFisher’s exact test was used to compare the proportion of rabbits with diarrhea in indicated group vs C227.