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. 2014 Jan 20;15:48. doi: 10.1186/1471-2164-15-48

Table 4.

Enrichment of gene groups up-regulated in muscle-less humeri based on GO terms under subontologies biological process and cellular component

Gene ontology: biological process Gene count in study Enrichment 1
Adhesion/Extracellular matrix
 32
 1.99 × 10-10 to 0.0842
  GO:0007155: Cell adhesion
 41
 1.99E-10
  GO:0022610: Biological adhesion
 41
 2.12E-10
  GO:0007156: Homophilic cell adhesion
 15
 4.95 × 10-7
  GO:0016337: Cell-cell adhesion
 19
 9.38 × 10-6
  GO:0043062: Extracellular structure organization
 9
 0.0223
  GO:0030198: Extracellular matrix organisation
 6
 0.0842
Cell signalling
 33
 3.45 × 10-9 to 0.0148
  GO:0007267: Cell-cell signalling
 27
 3.45 × 10-9
  GO:0007154: Cell communication
 33
 2.05 × 10-9
  GO:0007223: Wnt receptor signalling pathway, calcium modulating pathway
 7
 0.0092
  GO:0016055: Wnt receptor signalling pathway
 4
 0.0104
  GO:0008589: Regulation of smoothened signalling pathway
 9
 0.0105
  GO:0010648: Negative regulation of smoothened signalling pathway
 4
 0.0135
  GO:0048010: Vascular endothelial growth factor receptor signalling pathway
 10
 0.0288
  GO:0007169: Transmembrane receptor protein tyrosine kinase signalling pathway
 3
 0.0402
  GO:0007167: Enzyme linked receptor protein signalling pathway
 12
 0.0051
  GO:0007165: Signal transduction
 80
 0.0148
Development/Differentiation
 [34]
 4.38 × 10-6 to 0.0083
  GO:0048731: System development
 78
 4.38 × 10-6
  GO:0048856: Anatomical structure development
 81
 8.42 × 10-6
  GO:0007275: Multicellular organismal development
 87
 6.80 × 10-5
  GO:0048468: Cell development
 31
 8.17 × 10-5
  GO:0032502: Developmental process
 91
 1.82 × 10-4
  GO:0048869: Cellular developmental process
 59
 5.41 × 10-4
  GO:0030154: Cell differentiation
 57
 5.74 × 10-4
  GO:0048513: Organ development
 56
 0.0036
  GO:0045595: Regulation of cell differentiation
 18
 0.0083
Gene ontology: cellular component
 Gene count in study
 Enrichment 1
Extracellular region
 35
 2.34 × 10-10 to 0.022
  GO:0005576: Extracellular region
 81
 2.34 × 10-10
  GO:0044421: Extracellular region part
 43
 2.70 × 10-7
  GO:0031012: Extracellular matrix
 22
 1.16 × 10-5
  GO:0005578: Proteinaceous extracellular matrix
 21
 2.14 × 10-5
  GO:0005615: Extracellular space
 24
 0.0020
  GO:0044420: Extracellular matrix part
 7
 0.0202
Membrane association
 227
 2.46 × 10-16 to 1.01 × 10-6
  GO:0005886: Plasma membrane
 134
 2.46 × 10-16
  GO:0031224: Intrinsic to membrane
 191
 1.07 × 10-8
  GO:0044425: Membrane part
 215
 2.08 × 10-8
  GO:0016020: Membrane
 226
 7.80 × 10-8
  GO:0031224: Intrinsic to membrane 178 1.01 × 10-6

1P-value of enrichment of GO terms using DAVID analysis software; similar results were found with GOstat.